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Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria

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dc.contributor.authorPrieto Prieto, Laura Danielaspa
dc.contributor.authorVargas Borda , Lina Mariaspa
dc.contributor.authorJaramillo Hernández, Dumar Alexander
dc.date.accessioned2021-12-15T00:00:00Z
dc.date.accessioned2024-09-23T20:46:38Z
dc.date.available2021-12-15T00:00:00Z
dc.date.available2024-09-23T20:46:38Z
dc.date.issued2021-12-15
dc.description.abstractLas vacunas son el pilar fundamental de la medicina preventiva y la base para posibles planes de control y/o erradicación de enfermedades, especialmente las infecciosas. Los parásitos internos en los animales de producción y de compañía continúan siendo una de las principales amenazas para la salud y el bienestar animal con importantes implicaciones económicas, además de su impacto en la salud pública mundial. Su control se ha basado casi exclusivamente en fármacos quimioterápicos, que desde hace varios años han perdido su eficacia y existen claros ejemplos de resistencia parasitaria a ellos. Hay pocos ejemplos comerciales de vacunas de parásitos gastrointestinales disponibles comercialmente para su uso en la práctica de la Medicina Veterinaria. Esta revisión describe algunos ejemplos comerciales de vacunas gastrointestinales antiparasitarias para su formulación en la práctica médica veterinaria, visto desde la perspectiva de “las generaciones de vacunas” y respaldado por estudios clínicos experimentales de antígenos prometedores para el control profiláctico de ciertos agentes parasitarios gastrointestinales de interés en salud pública principalmente. Hasta la fecha, está disponible con ciertas limitaciones comerciales en algunos países europeos y oceánicos Barbervax® y en países sudamericanos Providean® Hidatil EG95 para uso en rumiantes para el control de Haemonchus contortus y Echinococcus granulosus, respectivamente; en algunos países de América y África, Cysvax™ está disponible para el control de Taenia solium en cerdos; y en el mundo con muy pocas limitaciones, una serie de vacunas comerciales para el control de la coccidosis como la Eimeria spp. en la industria avícola: pavos, pollos de engorde y gallinas ponedoras (ej: CocciVac®, Immucox®, Paracox®, entre otros). Existe la necesidad de tener estos tipos de vacunas en todos los países donde estos parásitos gastrointestinales son endémicos y de esta manera brindar opciones para su control, por consiguiente, una serie de inversiones económicas son necesarias para apoyar el desarrollo técnico-científico en torno al desarrollo de nuevos biológicos (nueva generaciones de vacunas) efectivos y seguros para el control de los parásitos internos más relevantes en animales de producción y de compañía.spa
dc.description.abstractVaccines are the fundamental pillar of preventive medicine and the basis for possible control and/or eradication of disease plans, especially infectious diseases. Internal parasites in production and companion animals continue to be one of the main threats to animal health and welfare with important economic implications, in addition to its impact on global public health. Its control has been based almost exclusively on chemotherapeutic drugs, which for several years have lost their efficacy and there are clear examples of parasitic resistance to them. Even so, few commercial examples of gastrointestinal parasite vaccines are commercially available for use in the practice of Veterinary Medicine. This review describes some commercial examples of gastrointestinal antiparasitic vaccines for their formulation in veterinary medical practice seen from the perspective of “the generations of vaccines'' and supported by experimental clinical studies of promising antigens for the prophylactic control of certain gastrointestinal parasitic agents of interest in public health mainly. To date, it is available with certain commercial limitations in some European and Australian countries Barbervax® and in South American countries Providean® Hidatil EG95 for use in ruminants for the control of Haemonchus contortus and Echinococcus granulosus, respectively; in some countries in America and Africa, Cysvax™ is available for the control of Taenia solium in pigs and in the world with very few limitations, a series of commercial vaccines for the control of coccidosis (Eimeria spp.) in poultry industry: turkeys, broilers and laying hens (e.g., CocciVac®, Immucox®, Paracox®, among others). There is a need to provide this type of vaccine to all countries where these gastrointestinal parasites are endemic and, in this way, provide options for their control. As well as a series of economic investments is highly necessary to support technical-scientific development around development of new effective and safe biologicals (new generations of vaccines) for the control of the most relevant internal parasites in production and companion animals.eng
dc.format.mimetypeapplication/pdfspa
dc.identifier.doi10.22579/22484817.879
dc.identifier.eissn2248-4817
dc.identifier.urihttps://repositorio.unillanos.edu.co/handle/001/4367
dc.identifier.urlhttps://doi.org/10.22579/22484817.879
dc.language.isospaspa
dc.publisherUniversidad de los Llanosspa
dc.relation.bitstreamhttps://revistas.unillanos.edu.co/index.php/sistemasagroecologicos/article/download/879/945
dc.relation.citationeditionNúm. 2 , Año 2021 : Julio-Diciembrespa
dc.relation.citationendpage96
dc.relation.citationissue2spa
dc.relation.citationstartpage74
dc.relation.citationvolume12spa
dc.relation.ispartofjournalRevista Sistemas de Producción Agroecológicosspa
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dc.rightsRevista Sistemas de Producción Agroecológicos - 2021spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourcehttps://revistas.unillanos.edu.co/index.php/sistemasagroecologicos/article/view/879spa
dc.subjectInternal parasite managementeng
dc.subjectpublic healtheng
dc.subjectzoonoseeng
dc.subjectManejo integrado de parásitos internosspa
dc.subjectsalud públicaspa
dc.subjectzoonosisspa
dc.subjectManejo integrado de parasitas internosspa
dc.subjectsaúde públicaspa
dc.subjectzoonosespa
dc.titleLas generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinariaspa
dc.title.translatedThe generations of the vaccines: Case of gastrointestinal antiparasitic vaccines used in Veterinary Medicineeng
dc.typeArtículo de revistaspa
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