Publicación:
Toxoplasmosis, una parasitosis de importancia en salud pública

dc.contributor.advisorHernández Martínez, María Cristina
dc.contributor.authorNovoa Giraldo, Leidy Tatiana
dc.date.accessioned2023-11-22T15:12:38Z
dc.date.available2023-11-22T15:12:38Z
dc.date.issued2019
dc.descriptionIncluye tablas y figuras.spa
dc.description.abstractLa toxoplasmosis es causada por el Toxoplasma gondii, es una infección zoonótica que afecta hospederos intermediario y definitivos. Los felinos son los hospederos definitivos y es en donde se lleva a cabo la fase sexual del parásito, diseminando los quistes en el medio ambiente y favoreciendo de este modo la zoonosis. Esta es una enfermedad en el hombre, puede generar daño en diferentes tejidos, puede atravesar la barrea trasplacentaria, lo que lo convierte en un factor de riesgo para las mujeres gestantes y recién nacidos. T. gondii se encuentra distribuido a nivel mundial, por su morfología y patogenia tiene la capacidad de infectar casi cualquier mamífero o ave, facilitando su distribución. La infección puede ser sintomática o asintomática, esto de acuerdo al estadio en que se encuentre cuando infecta al ser humano, a pesar de esto en Colombia no es considerada como una enfermedad de reporte obligatorio.spa
dc.description.abstractToxoplasmosis is caused by Toxoplasma gondii, it is a zoonotic infection that affects intermediate and definitive hosts. The felines are the definitive hosts and it is where the sexual phase of the parasite takes place, spreading the cysts in the environment and thus favoring zoonosis. This is a disease in man, it can cause damage to different tissues, it can cross the transplacental barrier, which makes it a risk factor for pregnant women and newborns. T. gondii is distributed worldwide, due to its morphology and pathogenesis it has the capacity to infect almost any mammal or bird, facilitating its distribution. The infection can be symptomatic or asymptomatic, this according to the stage in which it is when it infects the human being, although this in Colombia is not considered as a disease of mandatory reporting.eng
dc.description.degreelevelPregradospa
dc.description.degreenameMedico(a) Veterinario(a) Zootecnistaspa
dc.description.programMedicina Veterinaria y Zootecniaspa
dc.description.tableofcontentsIntroducción. -- Objetivos. -- Objetivo general. -- Objetivos específicos. -- Revisión bibliográfica. -- Historia del toxoplasma gondii. -- Toxoplasma gondii. -- Morfología. -- Ciclo de vida del toxoplasma gondii. -- Epidemiología. -- Patogenia. -- Diagnóstico. -- Signos clínicos. -- Tratamiento. -- Situación en Colombia . -- Conclusiones y recomendaciones. -- Bibliografía.spa
dc.format.extent63 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.citationNovoa Giraldo, L. (2019). Toxoplasmosis, una parasitosis de importancia en salud pública [Trabajo de grado, Universidad de los Llanos]. Repositorio digital Universidad de los Llanos.spa
dc.identifier.instnameUniversidad de los Llanosspa
dc.identifier.reponameRepositorio digital Universidad de los Llanosspa
dc.identifier.repourlhttps://repositorio.unillanos.edu.co/spa
dc.identifier.urihttps://repositorio.unillanos.edu.co/handle/001/3210
dc.language.isospaspa
dc.publisherUniversidad de los Llanosspa
dc.publisher.facultyFacultad de Ciencias Agropecuarias y Recursos Naturalesspa
dc.publisher.placeVillavicenciospa
dc.relation.referencesAfonso E, Thulliez P, Gilot-Fromont E. 2010. Local meteorological conditions, dynamics of seroconversion to Toxoplasma gondii in cats (Felis catus) and oocyst burden in a rural environment. Epidemiology and Infection, 138(8), 1105–1113. http://doi.org/10.1017/S0950268809991270spa
dc.relation.referencesAjioka JW, Morrissette NS. 2009. A century of Toxoplasma research. International Journal for Parasitology, 39(8), 859–860. En: 30-04-2019 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693343/spa
dc.relation.referencesAlexander DL, Mital J, Ward GE, Bradley P, Boothroyd JC. 2005. Identification of the moving junction complex of Toxoplasma gondii: a colaboration between distinct secretory organelles. PloS Pathogens, 1(2): e17.spa
dc.relation.referencesAlvarado-Socarras JL, Meneses-Silvera K, Zarate-Vergara AC, Guerrero- Gómez C, Rodríguez-Morales AJ. 2017. Not everything is Zika: Congenital toxoplasmosis, still prevalent in Colombia. Revista peruana de medicina experimental y salud pública, 34(2), 332–336. http://doi.org/10.17843/rpmesp.2017.342.2697spa
dc.relation.referencesAnderson-White B, Beck JR, Chen CT, Meissner M, Bradley PB, Gubbels MJ. 2014. Cytoskeleton assembly in Toxoplasma gondii cell division.spa
dc.relation.referencesAnderson-White BR, Ivey FD, Cheng K, Szatanek T, Lorestani A. 2010. A family of intermediate filament-like proteins is sequentially assembled into the cytoskeleton of Toxoplasma gondii. Cellular Microbiology. 13: 18–31spa
dc.relation.referencesAndrews KT, Fisher G, Skinner-Adams TS. 2014. Drug repurposing and human parasitic protozoan diseases. International Journal for Parasitology: Drugs and Drug Resistance, 4(2), 95–111. http://doi.org/10.1016/j.ijpddr.2014.02.002spa
dc.relation.referencesAntczak M, Dzitko K, Długońska H. 2016. Human toxoplasmosis–Searching for novel chemotherapeutics. Biomedicine and Pharmacotherapy, 82, 677– 684. http://doi.org/10.1016/j.biopha.2016.05.041spa
dc.relation.referencesAramini JJ, Stephen C, Dubey JP, Engelstoft C, Schwantje H, Ribble CS. 1999. Potential contamination of drinking water with Toxoplasma gondii oocysts. Epidemiology and Infection, 122(2), 305–315. Retrieved from https://www.cambridge.org/core/journals/epidemiology-andinfection/article/potential-contamination-of-drinking-water-with-toxoplasmagondii-oocysts/57804A633FBF090660039E91B43EE470#spa
dc.relation.referencesAvasthi P, Marshall W. 2013. Ciliary secretion: switching the cellular antenna to ‘transmit’. Curr Biology 23:R471–R473.doi:10.1016/j.cub.2013.04.056.spa
dc.relation.referencesAzimzadeh J, Marshall WF. 2010. Building the centriole. Current Biology 20:R816–R825. doi:10.1016/j.cub.2010.08.010.spa
dc.relation.referencesAzimzadeh J, Bornens M. 2007. Structure and duplication of the centrosome. Journal Cell Science. 120:2139–2142.doi:10.1242/jcs.005231spa
dc.relation.referencesBalasundaram MB, Andavar R, Palaniswamy M, Venkatapathy N. 2010. Outbreak of acquired ocular toxoplasmosis involving 248 patients. Archives of Ophthalmology, 128(1), 28–32. En: 02-05-2019. http://doi.org/10.1001/archophthalmol.2009.354spa
dc.relation.referencesBarrera AM, Castiblanco P, Gómez-Marín JE, López MC, Ruiz A, Moncada L, Corredor A. 2002. Toxoplasmosis adquirida durante el embarazo, en el Instituto Materno Infantil en Bogotá. Revista de Salud Pública, 4(3), 286–293.spa
dc.relation.referencesBeghetto E, Spadoni A, Bruno L, Buffolano W, Gargano N. 2006. Chimeric antigens of Toxoplasma gondii: Toward standardization of toxoplasmosis serodiagnosis using recombinant products. Journal of Clinical Microbiology, 44(6), 2133–2140. http://doi.org/10.1128/JCM.00237-06spa
dc.relation.referencesBenavides J, Fernández M, Castaño P, Ferreras MC, Ortega-Mora L, Pérez V. 2017. Ovine Toxoplasmosis: A New Look at its Pathogenesis. Journal of Comparative Pathology, 157(1), 34–38. En: 02-05-2019. http://doi.org/10.1016/j.jcpa.2017.04.003spa
dc.relation.referencesBenson A, Pifer R, Behrendt CL, HooperLV, Yarovinsky F. 2009. Gut commensal bacteria direct a protective immune response against Toxoplasma gondii. Cell Host Microbe. 6:187– 196.doi:10.1016/j.chom.2009.06.005.spa
dc.relation.referencesBerger F, Goulet V, Le Strat Y, Desenclos JC. 2009. Toxoplasmosis among pregnant women in France: Risk factors and change of prevalence between 1995 and 2003. Revue d’Epidemiologie et de Sante Publique, 57(4), 241– 248. http://doi.org/10.1016/j.respe.2009.03.006spa
dc.relation.referencesBertranpetit E, Jombart T, Paradis E, Pena H, Dubey J, Su C, Ajzenberg, D. 2017. Phylogeography of Toxoplasma gondii points to a South American origin. Infection, Genetics and Evolution, 48, 150–155. En: 30-04-2019. http://doi.org/10.1016/j.meegid.2016.12.020spa
dc.relation.referencesBesteiro S, Bertrand-Michel J, Lebrun M, Vial H, Dubremetz JF. 2008. Lipidomic analysis of Toxoplasma gondii tachyzoites rhoptries: further insights into the role of cholesterol. Biochem. Journal. 415(1):87-96.spa
dc.relation.referencesBlack M, Boothroyd J. 2000. Lytic cycle of Toxoplasma gondii. Microbiology and Molecular Biology Reviews. 64(3), 607-‐623.spa
dc.relation.referencesBlader IJ, Coleman BI, Chen CT, Gubbels MJ. 2015. Lytic cycle of Toxoplasma gondii : 15 Years Later. Annual Review of Microbiology, 69(1), 463–485. http://doi.org/10.1146/annurev-micro-091014-104100spa
dc.relation.referencesBlader IJ, Saeij JP. 2009. Communication between Toxoplasma gondii and its host: Impact on parasite growth, development, immune evasion, and virulence. Apmis, 117(5–6), 458–476. http://doi.org/10.1111/j.1600- 0463.2009.02453.xspa
dc.relation.referencesBodaghi B, Touitou V, Fardeau C, Paris L, Lehoang P. 2012. Toxoplasmosis: New challenges for an old disease. Eye, 26(2), 241–244. http://doi.org/10.1038/eye.2011.331spa
dc.relation.referencesBorges IP, Castanheira LE, Barbosa BF, De Souza DLN, Da Silva RJ, Mineo JR, De Melo Rodrigues V. 2016. Anti-parasitic effect on Toxoplasma gondii induced by BnSP-7, a Lys49-phospholipase A2homologue from Bothrops pauloensis venom. Toxicon, 119, 84–91. En: 30-04-2019. http://doi.org/10.1016/j.toxicon.2016.05.010spa
dc.relation.referencesBradley PJ, Sibley LD. Rhoptries: 2007. an arsenal of secreted virulence factors. Curr. Op. Microbiol. 10(6):582-7.spa
dc.relation.referencesBuzoni-Gatel D, Schulthess J, Menard LC, Kasper LH. 2006. Mucosal defences against orally acquired protozoan parasites, emphasis on Toxoplasma gondii infections. Cellular Microbiology, 8(4), 535–544. http://doi.org/10.1111/j.1462-5822.2006.00692.xspa
dc.relation.referencesCampo D, Discuviche M, Blanco P, Montero Y, Orozco K, Assia Y. 2014. Detección de Toxoplasma gondii por amplificación del gen B1 en carnes de consume humano. Infectio, 18(3), 93-99.spa
dc.relation.referencesCarme B, Bissuel F, Ajzenberg D, Bouyne R, Aznar C, Bichat S, Darde ML. 2002. Severe acquired toxoplasmosis in immunocompetent adult patients in French Guiana severe acquired toxoplasmosis in immunocompetent adult patients in French Guiana. Journal of Clinical Microbiology, 40(11), 4037– 4044. http://doi.org/10.1128/JCM.40.11.4037spa
dc.relation.referencesCarral L, Kaufer F, Pardini L, Durlach R, Moré G, Venturini MC, Freuler C. 2018. Toxoplasmosis congénita: Diagnóstico serológico, RPC, aislamiento y caracterización molecular de Toxoplasma gondii. Revista Chilena de Infectología. 35 (1): 36-40.spa
dc.relation.referencesCastro AT, Góngora A, González ME. 2008. Sero-prevalencia de anticuerpos a Toxoplasma gondii en mujeres embarazadas de Villavicencio, Colombia. Orinoquia. 12: 91-100.spa
dc.relation.referencesChang S, Shan X, Li X, Fan W, Zhang SQ, Zhang J, Jiang N, Ma D, Mao Z. 2015. Toxoplasma gondii rhoptry protein ROP16 mediates partially SH-SY5Y cells apoptosis and cell cycle arrest by directing ser15/37 phosphorylation of p53. Int. J. Biol. Sci. 11(10):1215-25.spa
dc.relation.referencesChaparro JD, Cheng T, Tran UP, Andrade RM, Brenner SBT, Hwang G, Reed, SL. 2018. Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis. PLoS ONE, 13(3), 1–11. http://doi.org/10.1371/journal.pone.0193982spa
dc.relation.referencesChaudhry SA, Gad N, Koren G. 2014. Toxoplasmosis and pregnancy. Can Fam Physician 60:334 –336.spa
dc.relation.referencesChoi KM, Gang J, Yun J. 2008. Anti-Toxoplasma gondii RH strain activity of herbal extracts used in traditional medicine. International Journal of Antimicrobial Agents, 32(4), 360–362. En: 02-05-2019. http://doi.org/10.1016/j.ijantimicag.2008.04.012spa
dc.relation.referencesClough B, Frickel EM. 2017. The Toxoplasma Parasitophorous Vacuole: An Evolving Host–Parasite Frontier. Trends in Parasitology, 33(6), 473–488. http://doi.org/10.1016/j.pt.2017.02.007spa
dc.relation.referencesCohen SB, Denkers EY. 2015. The gut mucosal immune response to Toxoplasma gondii. Parasite Immunology, 37(3), 108–117. http://doi.org/10.1111/pim.12164spa
dc.relation.referencesColeman JW. 2001. Nitric oxide in immunity and inflammation. International Immunopharmacology, 1(8), 1397–1406. http://doi.org/10.1016/S15675769(01)00086-8spa
dc.relation.referencesConnolly MP, Goodwin E, Schey C, Zummo J. 2017. Toxoplasmic encephalitis relapse rates with pyrimethamine-based therapy: systematic review and meta-analysis. Pathogens and Global Health, 111(1), 31–44. http://doi.org/10.1080/20477724.2016.1273597spa
dc.relation.referencesCook AJ, Gilbert RE, Buffolano W, Zufferey J, Petersen E, Jenum PA, Dunn D. 2000. Sources of toxoplasma infection in pregnant women: European multicentre case-control study. European Research Network on Congenital Toxoplasmosis. BMJ (Clinical Research Ed.), 321(7254), 142–147. http://doi.org/10.1136/bmj.321.7254.142spa
dc.relation.referencesCortés AD, Aguirre N. 2018. Toxoplasmosis aguda diseminada fatal en paciente adulto sin inmunodeficiencia proveniente del pacífico colombiano. Biomédica, 38(4), 2–22. http://doi.org/http://dx.doi.org/10.7705/biomedica.v33i4.836spa
dc.relation.referencesCortés JA, Gómez-Marín JE, Silva PI, Arévalo L, Arévalo I, Álvarez MI, Gómez PI. 2012. Guía de atención integral para la prevención, detección temprana y tratamiento de las complicaciones del embarazo, parto y puerperio: sección toxoplasmosis en el embarazo. Infectio, 16(4), 230–246. http://doi.org/10.1016/S0123-9392(12)70018-8spa
dc.relation.referencesCortez E, Stumbo AC, Oliveira M, Barbosa HS, Carvalho L. 2009. Statins inhibit Toxoplasma gondii multiplication in macrophages in vitro. International Journal of Antimicrobial Agents, 33(2), 183–192. En: 02-05-2019. http://doi.org/10.1016/j.ijantimicag.2008.07.026spa
dc.relation.referencesDabritz HA, Miller MA, Gardner IA, Packham AE, Atwill ER, Conrad PA. 2008. Risk factors for Toxoplasma gondii infection in wild rodents from Central Coastal California and a review of T. gondii prevalence in rodents. Journal of Parasitology, 94(3), 675–683. http://doi.org/10.1645/GE-1342.1spa
dc.relation.referencesDard C, Fricker-Hidalgo H, Brenier-Pinchart MP, Pelloux H. 2016. Review. Relevance of and New Developments in Serology for Toxoplasmosis. Trends Parasitology. June; 32(6)492–506.spa
dc.relation.referencesDayan V, Sotelo V, Delfina V, Delgado N, Rodríguez C, Suanes C, Benech A. 2015. Ischemia-induced model of diastolic dysfunction in sheep. Journal of Investigative Surgery, 28(2), 71–76. En: 02-05-2019. http://doi.org/10.3109/08941939.2014.970303spa
dc.relation.referencesda Silva PC, Shiraishi CS, Silva AV, Goncalves GF, Sant'Ana de M, Araujo EJ. 2010. Toxoplasma gondii: a morphometric analysis of the wall and epithelial cells of pigs intestine. Exp Parasitology.125:380–3.spa
dc.relation.referencesDe Moura AA, Kayano AM, Oliveira GA, Setúbal SS, Ribeiro JG, Barros NB, Calderon LA. 2014. Purification and biochemical characterization of three myotoxins from Bothrops mattogrossensis snake venom with toxicity against Leishmania and tumor cells. BioMedic Research International, 1–13. http://doi.org/10.1155/2014/195356spa
dc.relation.referencesDe Moura L, García Bahía-Oliveira LM, Wada MY, Jones JL, Tuboi SH, Carmo, EH, Garrett DO. 2006. Waterborne toxoplasmosis, Brazil, from field to gene. Emerging Infectious Diseases, 12(2), 326–329. En: 30-04-2019. http://doi.org/10.3201/eid1202.041115spa
dc.relation.referencesDe Oliveira TC, Silva DA, Rostkowska C, Béla SR, Ferro EAV, Magalhães PM, Mineo JR. 2009. Toxoplasma gondii: Effects of Artemisia annua L. on susceptibility to infection in experimental models in vitro and in vivo. Experimental Parasitology, 122(3), 233–241. http://doi.org/10.1016/j.exppara.2009.04.010spa
dc.relation.referencesDelair E, Monnet D, Grabar S, Dupouy-Camet J, Yera H, Brézin AP. 2008. Respective roles of acquired and congenital infections in presumed ocular toxoplasmosis. American Journal of Ophthalmology, 146(6), 851–855. http://doi.org/10.1016/j.ajo.2008.06.027spa
dc.relation.referencesDhakal R, Gajurel K, Pomares C, Talucod J, Press CJ, Montoya JG. 2015. Significance of a positive toxoplasma immunoglobulin M test result in the United States. Journal of Clinical Microbiology, 53(11), 3601–3605. http://doi.org/10.1128/JCM.01663-15spa
dc.relation.referencesDe Egan CE, Craven MD, Leng J, Mack M, Simpson KW, Denkers EY. 2009. Los linfocitos intra-epiteliales dependientes de CCR2 mediana de la patología intestinal inflamatoria durante la infección por Toxoplasma gondii. Mucosal Immunology 2 :527 - 535 . doi: 10.1038/mi.2009.105spa
dc.relation.referencesDi Cristina M, Dou Z, Lunghi M, Kannan G, Huynh MH, McGovern OL, Carruthers VB. 2017. Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection. Nature Microbiology, 2(June). http://doi.org/10.1038/nmicrobiol.2017.96spa
dc.relation.referencesDíaz JMP, Rey LKP, Carvajal DR. 2015. Infección por toxoplasma: panorama actual. Spei Domus, 11(22), 47–56. http://doi.org/10.16925/sp.v11i22.1154spa
dc.relation.referencesDonald RGK. 2007. Toxoplasma as a model system for apicomplexan drug discovery. In Toxoplasma gondii the model Apicomplexan: Perspectives and methods (pp. 505–539). Academic Press. http://doi.org/10.1016/B978012369542-0/50021-0spa
dc.relation.referencesDuarte I. 2013. Modelado de la propagación de Toxoplasma gondii. Tesis Doctorado en ciencia y tecnología. Universidad Nacional de General Sarmiento.spa
dc.relation.referencesDubey JP. 1988. Long-term persistence of Toxoplasma gondii in tissues of pigs inoculated with T. gondii oocysts and effect of freezing on viability of tissue cysts in pork. American Journal of Veterinary Research, 49(6), 910– 913spa
dc.relation.referencesDubey JP, Kotula AW, Sharar A, Andrews CD, Lindsay DS. 1990. Effect of high temperature on infectivity of Toxoplasma gondii tissue cysts in Pork. Journal of Parasitology, 76(2), 201–204. http://doi.org/10.2307/3283016spa
dc.relation.referencesDubey JP, Speer CA, Shen SK, Kwon OCH, Blixt JA 1997. Oocyst-induced murine toxoplasmosis: lefe cycle, pathogenicity, and stage conversion in mice fed Toxoplasma gondii oocysts. Journal Parasitology. 82: 870-872.spa
dc.relation.referencesDubey JP, Hill DE, Jones JL, Hightower AW, Kirkland E, Roberts JM, Gamble HR. 2005. Prevalence of viable Toxoplasma gondii in beef, chicken, and pork from retail meat stores in the United States: Risk assessment to consumers. Journal of Parasitology, 91(5), 1082–1093. http://doi.org/10.1645/GE-683.1spa
dc.relation.referencesDubey JP, Jones JL. 2008. Toxoplasma gondii infection in humans and animals in the United States. International Journal Parasitology; 38: 1257– 1278.spa
dc.relation.referencesDubey JP. 2009. History of the discovery of the life cycle of Toxoplasma gondii. International Journal for Parasitology, 39(8), 877–882. En: 30-04-2019 http://doi.org/10.1016/j.ijpara.2009.01.005spa
dc.relation.referencesDubey JP. 2010. Toxoplasmosis of animals and humans (Second Edition). Beltville, Maryland, USA: CRC Press, Inc.spa
dc.relation.referencesubey JP, Ferreira LR, Martins J, Jones JL. 2011. Sporulation and survival of Toxoplasma gondii oocysts in different types of commercial cat litter. Journal of Parasitology, 97(5), 751–754. http://doi.org/10.1645/GE-2774.1spa
dc.relation.referencesDubey JP. 2016. Toxoplasmosis of animals and humans (2nd Edition). Boca Raton, FL 33431: CRC Press.spa
dc.relation.referencesDzib-Paredes GF, Rosado-Aguilar JA, Acosta-Viana KY, Ortega-Pacheco A, Hernández-Cortázar IB, Guzman-Marín E, Jiménez-Coello M. 2016. Seroprevalence and parasite load of Toxoplasma gondii in Mexican hairless pig (Sus scrofa) tissues from the Southeast of Mexico. Veterinary Parasitology. Oct 15; 229:45-49. doi: 10.1016/j.vetpar.2016.09.016.spa
dc.relation.referencesElbez‐Rubinstein A, Ajzenberg D, Dardé M, Cohen R, Dumètre A, Yera H, Thulliez P. 2009. Congenital Toxoplasmosis and Reinfection during Pregnancy: Case Report, Strain Characterization, Experimental Model of Reinfection, and Review. The Journal of Infectious Diseases, 199(2), 280– 285. http://doi.org/10.1086/595793spa
dc.relation.referencesFarrell M, Gubbels MJ. 2014. The Toxoplasma gondii kinetochore is required for centrosome association with the centrocone (spindle pole). Cellular Microbiology. 16:78–94.doi:10.1111/cmi.12185spa
dc.relation.referencesFerguson DJP, Dubremetz JF. 2014. Capítulo 2 - The ultrastructure of Toxoplasma gondii. The Model Apicomplexan - Perspectives and Methods, Pages 19-59 (2° edition). Academic press. https://doi.org/10.1016/B978-0-12396481-6.00002-7spa
dc.relation.referencesFerguson DJP. 2009. Identification of faecal transmission of Toxoplasma gondii: Small science, large characters. International Journal for Parasitology, 39(8), 871–875. http://doi.org/10.1016/j.ijpara.2009.01.003spa
dc.relation.referencesFeustel SM, Meissner M, Liesenfeld O. 2012. Toxoplasma gondii and the blood-brain barrier. Virulence, 3(2), 182–192. http://doi.org/10.4161/viru.19004spa
dc.relation.referencesFrancia ME, Striepen B. 2014. Cell division in apicomplexan parasites. Nature Reviews Microbiology, 12(2), 125–136. http://doi.org/10.1038/nrmicro3184spa
dc.relation.referencesFranco EN. 2015. Prevalencia y factores asociados a la infección por Toxoplasma gondii en carne procedente de plantas de beneficio animal con destino nacional. Tesis Maestría Salud Pública. Facultad de Medicina. Universidad Nacional de Colombiaspa
dc.relation.referencesFrenkel J, Friedlander S. 1951. Toxoplasmosis. Pathology of neonatal disease. Pathogenesis, diagnosis and treatment. PHS publication 141. Government Printing Office, Washington, D.C.spa
dc.relation.referencesFrenkel JK, Dubey JP, Miller NL. 1970. Toxoplasma gondii in cats: fecal stages identified as coccidian oocysts. Science, 167(3919), 893–896. http://doi.org/10.1126/science .167.3919.893spa
dc.relation.referencesFurtado JM, Bharadwaj AS, Chipps TJ, Pan Y, Ashander LM, Smith JR. 2012. Toxoplasma gondii tachyzoites cross retinal endothelium assisted by intercellular adhesion molecule-1 in vitro. Immunology and Cell Biology, 90(9), 912–915. http://doi.org/10.1038/icb.2012.21spa
dc.relation.referencesGao XJ, Zhao ZJ, He ZH, Wang T, Yang TB, Chen XG, Lun ZR. 2012. Toxoplasma gondii infection in pregnant women in China. Parasitology, 139(2), 139–147. http://doi.org/10.1017/S0031182011001880spa
dc.relation.referencesGarcía FR, Fundora IM. 2014. Importancia y factibilidad del diagnóstico ambiental de Toxoplasma gondii en Cuba. Revista Cubana de Salud, 40(2), 286–289. En: http://scielo.sld.cu/scielo.php?script=sci_arttextypid=S086434662014000200014spa
dc.relation.referencesGarweg JG, Stanford MR. 2013. Therapy for ocular toxoplasmosis - The future. Ocular Immunology and Inflammation, 21(4), 300–305. http://doi.org/10.3109/09273948.2013.779724spa
dc.relation.referencesGeorgiev SV. 1994. Management of Toxoplasmosis. Drugs, 48(2), 179–188. http://doi.org/10.2165/00003495-199448020-00005spa
dc.relation.referencesGilbert RE, Freeman K, Lago EG, Bahia-Oliveira LMG, Tan HK, Wallon M, Cortina-Borja M. 2008. Ocular sequelae of congenital toxoplasmosis in Brazil compared with Europe. PLoS Neglected Tropical Diseases, 2(8), 8–14. http://doi.org/10.1371/journal.pntd.0000277spa
dc.relation.referencesGilbert R, Petersen E. 2017. Toxoplasmosis and pregnancy. En: 02-05-2019. http://enjoypregnancyclub.com/wp-content/uploads/2017/05/Toxoplasmosis and pregnancy.pdfspa
dc.relation.referencesGolkar M, Azadmanesh K, Khalili G, Khoshkholgh-Sima B, Babaie J, Mercier C, Cesbron-Delauw MF. 2008. Serodiagnosis of recently acquired Toxoplasma gondii infection in pregnant women using enzyme-linked immunosorbent assays with a recombinant dense granule GRA6 protein. Diagnostic Microbiology and Infectious Disease, 61(1), 31–39. http://doi.org/10.1016/j.diagmicrobio.2007.09.003spa
dc.relation.referencesGómez de León CT, Díaz RD, Mendoza G, González S, Ambrosio JR, Mondragón R. 2014. Proteomic characterization of the subpellicular cytoskeleton of Toxoplasma gondii tachyzoites. Journal Proteomics Dec 5;111: 86-99. doi: 10.1016/j.jprot.2014.03.008. Epub Mar 21.spa
dc.relation.referencesGómez-Marín JE, de-la-Torre A, Ángel-Muller E, Rubio J, Arenas J, Osorio E, Castaño G. 2011. First colombian multicentric newborn screening for congenital toxoplasmosis. PLoS Neglected Tropical Diseases, 5(5). http://doi.org/10.1371/journal.pntd.0001195spa
dc.relation.referencesGómez JE. 2008. Toxoplasmosis: Nuevos Conceptos. In Veterinaria argentina (IV Edición, pp. 1–6). Argentina: INTA, FAO. En: 30-04-2019. http://doi.org/10.2134/ael2015.10.0007spa
dc.relation.referencesGómez JE, Castaño JC, Montoya-Londoño MT, Loango N, López C, Sarmiento MC, Pinzón L. 2000. Toxoplasmosis congénita en Colombia. Revista Colombiana de Pediatría, 35(1), 1–5.spa
dc.relation.referencesGoodson SG, Qiu Y, Sutton KA, Xie G, Jia W, O’Brien DA. 2012. Metabolic substrates exhibit differential effects on functional parameters of mouse sperm capacitation. Biology of Reproduction, 87(3). En: 02-05-2019. http://doi.org/10.1095/biolreprod.112.102673spa
dc.relation.referencesGras L, Gilbert RE, Wallon M, Peyron F, Cortina-Borja M. 2004. Duration of the IgM response in women acquiring Toxoplasma gondii during pregnancy: Implications for clinical practice and cross-sectional incidence studies. Epidemiology and Infection, 132(3), 541–548. http://doi.org/10.1017/S0950268803001948spa
dc.relation.referencesGubbels MJ, Duraisingh MT. 2012. Evolution of apicomplexan secretory organelles. International Journal for Parasitology, 42(12), 1071–1081. http://doi.org/10.1016/j.ijpara.2012.09.009spa
dc.relation.referencesGuo M, Lambertini E, Buchanan RL, Dubey JP, Hill DE, Gamble HR, Pradhan, AK. 2017. Quantifying the risk of human Toxoplasma gondii infection due to consumption of fresh pork in the United States. Food Control, 73, 1210–1222. http://doi.org/10.1016/j.foodcont.2016.10.038spa
dc.relation.referencesHalonen SK, Weiss LM. 2013. Toxoplasmosis. Handb Clinical Neurology; 114: 125-45. doi: 10.1016 / B978-0-444-53490-3.00008-X.spa
dc.relation.referencesHalos L, Thébault A, Aubert D, Thomas M, Perret C, Geers R, Villena I. 2010. An innovative survey underlining the significant level of contamination by Toxoplasma gondii of ovine meat consumed in France. International Journal for Parasitology, 40(2), 193–200. http://doi.org/10.1016/j.ijpara.2009.06.009spa
dc.relation.referencesHaraldsen JD, Liu G, Botting CH, Walton JAG, Storm J. 2009. Identificación de conoidina A como un inhibidor covalente de la peroxiredoxina II. Org Biomo Chem 7: 3040-3048.spa
dc.relation.referencesHarrell M, Carvounis PE. 2014. Current treatment of toxoplasma retinochoroiditis: an evidencebased review. Journal Ophthalmology: 273506.spa
dc.relation.referencesHehl AB, Basso WU, Lippuner C, Ramakrishnan C, Okoniewski M, Walker RA, Grigg ME, Smith NC, Deplazes P. 2015. La expansión asexual de los merozoítos de Toxoplasma gondii es distinta de los taquizoítos y conlleva la expresión de familias de genes no superpuestos para unir, invadir y replicar en enterocitos felinos. BMC Genomics 16: 66. doi: 10.1186 / s12864-0151225-xspa
dc.relation.referencesHernández-Cortázar I, Acosta-Viana K, Ortega-Pacheco A, Guzmán-Marín S, Aguilar-Caballero AJ, Jiménez-Coello M. 2015. Review. Toxoplasmosis in Mexico: epidemiological situation in humans and animals. Revista Institucional de Medicina Tropical. Sao Paulo. 57(2):93-103, March-April.spa
dc.relation.referencesHill DE, Dubey JP. 2018. Toxoplasma gondii. In Y. R. Ortega y C. R. Sterling (Eds.), Foodborne Parasites (pp. 119–138). Cham: Springer International Publishing. http://doi.org/10.1007/978-3-319-67664-7_6spa
dc.relation.referencesHodges ME, Scheumann N, Wickstead B, Langdale JA, Gaviota K. 2010. Reconstruyendo la historia evolutiva del centríolo a partir de componentes de proteínas. Journal Cellular Science 123: 1407 - 1413 .doi: 10.1242 / jcs.064873spa
dc.relation.referencesHoff EF, Carruthers VB. 2002. Is Toxoplasma egress the first step in invasion? Trends in Parasitology, 18(6), 251–255. http://doi.org/10.1016/S1471-4922(02)02240-7spa
dc.relation.referencesHolec-Gasior L , Ferra B, Drapała D, Lautenbach D, Kur J. 2012. A new MIC1- MAG1 recombinant chimeric antigen can be used instead of the Toxoplasma gondii lysate antigen in serodiagnosis of human toxoplasmosis. Clinical and Vaccine Immunology, 19(1), 57–63. http://doi.org/10.1128/CVI.05433-11spa
dc.relation.referencesHo-Woo Nam. 2009. GRA proteins of Toxoplasma gondii: maintenance of host-parasite interactions across the parasitophorous vacuolar membrane. Korean Journal Parasitology. 47: S29-37.spa
dc.relation.referencesHong SH, Le HA, Lee Y, Chung YH, Kim O. 2014. Anti-toxoplasmosis effect of Dictamnus dasycarpus extract against Toxoplasma gondii. Journal of Biomedical Research, 15(1), 7–11.spa
dc.relation.referencesHong SH, Kim HJ, Jeong Y, Cho SH, Lee WJ, Kim JT, Lee SE. 2017. Serological and molecular detection of Toxoplasma gondii and Babesia microti in the blood of rescued wild animals in Gangwon-do (Province), Korea. Korean. Journal of Parasitology, 55(2), 207–212. http://doi.org/10.3347/kjp.2017.55.2.207spa
dc.relation.referencesHu K, Johnson J, Florens L, Fraunholz M, Suravajjala S, Dilullo C, Yates J, Roos DS, Murray JM. 2006. Cytoskeletal components of an invasion machine--the apical complex of Toxoplasma gondii. PLoS Pathog. 2(2).spa
dc.relation.referencesHu K, Roos DS, Murray JM. 2002 Un nuevo polímero de tubulina forma el conoide de Toxoplasma gondii. Journal Celular Biology. 156: 1039-1050.spa
dc.relation.referencesHuang R, Que X, Hirata K, Brinen LS, Lee JH, Hansell E, Reed S. 2009. The cathepsin L of Toxoplasma gondii (TgCPL) and its endogenous macromolecular inhibitor, toxostatin. Molecular and Biochemical Parasitology, 164(1), 86–94. http://doi.org/10.1016/j.molbiopara.2008.11.012spa
dc.relation.referencesInnes EA. 2010. A brief history and overview of Toxoplasma gondii. Zoonoses and Public Health, 57(1), 1–7. http://doi.org/10.1111/j.18632378.2009.01276.xspa
dc.relation.referencesJacome J. 2007. Prevalencia de infección por Toxoplasma gondii en mujeres embarazadas, en Valledupar, Cesar año 2007. Tesis Maestría. Universidad del Magdalena.spa
dc.relation.referencesJayakumar PN, Chandrashekar HS, Ellika S. 2013. Chapter 4 – Imaging of parasitic infections of the central nervous system. Handbook of Clinical Neurology. Neuroparasitology and Tropical Neurology. 114:37–64.spa
dc.relation.referencesJiang JH, Jin CM, Kim YC, Kim HS, Park WC, Park H. 2008. Antitoxoplasmosis effects of oleuropein isolated from Fraxinus rhychophylla. Biological y Pharmaceutical Bulletin, 31(12), 2273–2276. En: 30-04-2019. http://doi.org/10.1248/bpb.31.2273spa
dc.relation.referencesJiménez-Coello M, Guzmán-Marín E, Ortega-Pacheco A, Acosta-Viana KY. 2011. Immunological status against Toxoplasma gondii in non-cat owners from an endemic region of Mexico. Vector Borne Zoonotic Dis. 11:1057-61.spa
dc.relation.referencesJokelainen P, Tagel M, Mõtus K, Viltrop A, Lassen B. 2017. Toxoplasma gondii seroprevalence in dairy and beef cattle: Large-scale epidemiological study in Estonia. Veterinary Parasitology. 15 March; 236:137–143.spa
dc.relation.referencesKafsack BFC, Pena JDO, Coppens I, Ravindran S, Boothroyd JC, Carruthers VB. 2009. Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells. Science (Vol. 323) En: 28-04-2019. http://doi.org/10.1126/science.1165740spa
dc.relation.referencesKamerkar S, Davis PH. 2012. Toxoplasma on the brain: Understanding hostpathogen interactions in chronic CNS infection. Journal Parasitology Research. Article ID 589295, 10 pages doi:10.1155/2012/589295spa
dc.relation.referencesKaplan JE, Benson C, Holmes KK, Brooks JT, Pau A, Masur H. 2009. HIV Medicine Association of the Infectious Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIVinfected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports, 58(RR-4), 1–207. http://www.ncbi.nlm.nih.gov/pubmed/19357635spa
dc.relation.referencesKavitha N, Noordin R, Chan KL, Sasidharan S. 2012. In vitro AntiToxoplasma gondii activity of root extract/fractions of Eurycoma longifolia Jack. BMC Complementary and Alternative Medicine, 12. http://doi.org/10.1186/1472-6882-12-91spa
dc.relation.referencesKieschnick H, Wakefield T, Narducci CA, Beckers C. 2001. Toxoplasma gondii Attachment to Host Cells Is Regulated by a Calmodulin-like Domain Protein Kinase. Journal of Biological Chemistry, 276(15), 12369–12377. http://doi.org/10.1074/jbc.M011045200spa
dc.relation.referencesKijlstra A, Jongert E. 2009. Toxoplasma-safe meat: close to reality? Trends in Parasitology, 25(1), 18–22. http://doi.org/10.1016/j.pt.2008.09.008spa
dc.relation.referencesKim K, Weiss LM. 2008. Toxoplasma: the next 100 years. Microbes and Infection, 10(9), 978–984. http://doi.org/10.1016/j.micinf.2008.07.015spa
dc.relation.referencesKim SJ, Scott IU, Brown GC. 2013. Interventions for toxoplasma retinochoroiditis: a report by the American Academy of Ophthalmology. Ophthalmology; 120: 371–378.spa
dc.relation.referencesKodjikian L, Hoigne I, Adam O, Jacquier P, Aebi-Ochsner C, Aebi C, Garweg J. 2004. Vertical transmission of toxoplasmosis from a chronically infected immunocompetent woman. The pediatric infectious disease journal (Vol. 23). Lyon, France. http://doi.org/10.1097/01.inf.0000115949.12206.69spa
dc.relation.referencesLachenmaier SM, Deli MA, Meissner M, Liesenfeld O. 2011. Intracellular transport of Toxoplasma gondii through the blood-brain barrier. Journal of Neuroimmunology, 232(1–2), 119–130. En: 02-05-2019. http://doi.org/10.1016/j.jneuroim.2010.10.029spa
dc.relation.referencesLebrun M, Carruthers VB, Cesbron-Delauw MF. 2014. Toxoplasma Gondii (Second Edition). The Model Apicomplexan - Perspectives and Method. Chapter 12 - Toxoplasma Secretory Proteins and Their Roles in Cell Invasion and Intracellular Survival. https://doi.org/10.1016/B978-0-12-396481-6.00012Xspa
dc.relation.referencesLehmann T, Marcet PL, Graham DH, Dahl ER, Dubey JP. 2006. Globalization and the population structure of Toxoplasma gondii. Proceedings of the National Academy of Sciences, 103(30), 11423–11428. En: 30-04-2019. http://doi.org/10.1073/pnas.0601438103spa
dc.relation.referencesLeón-Jaramillo EJ. 2018. Determinación de anticuerpos para Toxoplasma gondii en tigrillos (Leopardus pardalis) mantenidos en cautiverio en las regiones Costa, Sierra y oriente del Ecuador. Universidad central del Ecuador. En: http://www.dspace.uce.edu.ec/bitstream/25000/14883/4/T-UCE0014-060-2018.pdfspa
dc.relation.referencesLevaditi C, Schoen R, Sanchis Bayarri V. 1928. L'encéphalomyélite toxoplasmique chronique du lapin et de la souris. C. R. Seances Soc. Biol. Fil. 99:37-40.spa
dc.relation.referencesLi ZH, Ramakrishnan S, Striepen B, Moreno SNJ. 2013. Toxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin. PLoS Pathogens, 9(10). EDn: 30-04-2019. http://doi.org/10.1371/journal.ppat.1003665spa
dc.relation.referencesLi, XL, Wei HX, Zhang H, Peng HJ, Lindsay DS. 2014. A metanalysis on risks of adverse pregnancy outcomes in Toxoplasma gondii Infection. PLoS ONE, 9(5), e97775. http://doi.org/10.1371/journal.pone.0097775spa
dc.relation.referencesLiesenfeld O, Press C, Montoya JG, Gill R, Isaac-Renton JL, Hedman K, Remington JS. 1997. False-positive results in immunoglobulin M (IgM) toxoplasma antibody tests and importance of confirmatory testing: The platelia toxo IgM test. Journal of Clinical Microbiology, 35(1), 174–178.spa
dc.relation.referencesLindsay DS, Dubey JP. 2014. Toxoplasmosis in wild and domestic animals, p 194-209. In Weiss LM, Kim K (ed), Toxoplasma gondii: the model apicomplexan, 2nd ed. Elsevier, Amsterdam, The Netherlandsspa
dc.relation.referencesLiu Q, Singla LD, Zhou H. Vaccines against Toxoplasma gondii: status, challenges and future directions. Hum Vacc Immunother. 2012; 8: 1305–8.spa
dc.relation.referencesLópez-Yglesias AH, Burger E, Araujo A, Martin AT, Yarovinsky F. 2018. Tbet-independent Th1 response induces intestinal immunopathology during Toxoplasma gondii infection. Mucosal Immunology, (October 2017), 1–11. http://doi.org/10.1038/mi.2017.102spa
dc.relation.referencesLorenzi H, Khan A, Behnke MS, Namasivayam S, Swapna LS, Hadjithomas M, Sibley LD. 2016. Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes. Nature Communications, 7. http://doi.org/10.1038/ncomms10147spa
dc.relation.referencesMaenz M, Schlüter D, Liesenfeld O, Schares G, Gross U, Pleyer U. 2014. Ocular toxoplasmosis past, present and new aspects of an old disease, progress in retinal and eye Research, 39, 77–106. En: 28-04-2019 http://doi.org/10.1016/j.preteyeres.2013.12.005spa
dc.relation.referencesMaguiña C, Álvarez H, Carcelén A, Irrivaren J, Soto J, Cok E. 1998. Toxoplasmosis en Bartonellosis humana. Revista Médica Herediana, 9(3), 14-20. http://doi.org/10.20453/rmh.v9i1.564spa
dc.relation.referencesMeissner M, Ferguson JP, Frischknecht F. 2013. Invasion factors of apicomplexan parasites: Essential or redundant? Current Opinion in Microbiology, 16(4), 438–444. http://doi.org/10.1016/j.mib.2013.05.002spa
dc.relation.referencesMercier C, Cesbron-Delauw MF. 2015. Review. Toxoplasma secretory granules: one population or more? Trends in Parasitology. Feb;31(2):60–71.spa
dc.relation.referencesMiao KL, Zhang JZ, Dong Y, Xi YF. 2001. Research progress on the chemical compounds and pharmacology of Sophora flavescens. Natural Production Research, 13, 69–73.spa
dc.relation.referencesMiller CM, Boulter NR, Ikin RJ, Smith NC. 2009. The immunobiology of the innate response to Toxoplasma gondii. International Journal for Parasitology, 39(1), 23–39. http://doi.org/10.1016/j.ijpara.2008.08.002spa
dc.relation.referencesMimica F, Muñoz C, Torres M, Padilla O. 2015. Toxoplasmosis, zoonosis parasitaria prevalente en Chile: recuento y desafíos. Revista Chilena de Infectologia, vol 32spa
dc.relation.referencesMoncada PA, Montoya JG. 2012. Toxoplasmosis in the fetus and newborn: An update on prevalence, diagnosis and treatment. Expert Review of AntiInfective Therapy, 10(7), 815–828. http://doi.org/10.1586/eri.12.58spa
dc.relation.referencesMontealegre I, Valbuena Y, Cortes L, Flórez A. 2009. Seroprevalencia de la toxoplasmosis y factores relacionados con las enfermedades transmitidas por alimentos en trabajadores de plantas de beneficio animal en cinco ciudades capitales de Colombia. Nova - Publicación científica en Ciencias Biomédicas. ISSN: 1794-2470. 7:1-110.spa
dc.relation.referencesMorales JJ. 2007. Presencia de felinos domésticos como factores de riesgo para la presentación de infecciones por Toxoplasma gondii en caninos domésticos. Tesis Médico Veterinario. Lima, PE. Universidad Nacional Mayor de San Marcos. FMV. 47p.spa
dc.relation.referencesMorrissette N. 2015. Targeting toxoplasma tubules: tubulin, microtubules, and associated proteins in a human pathogen. Eukaryotic Cell. Volume 14 No. 1.spa
dc.relation.referencesMorrissette N, Gubbels MJ. 2014. Toxoplasma gondii (Second Edition). The Model Apicomplexan - Perspectives and Methods. Chapter 13 - The Toxoplasma Cytoskeleton: Structures, Proteins and Processes. Academic Press. https://doi.org/10.1016/B978-0-12-396481-6.00013-1spa
dc.relation.referencesMorrissette NS, Ajioka JW. 2009. The early years of Toxoplasma research: What’s past is prologue. International Journal for Parasitology, 39(8), 865– 869. En: https://www.ncbi.nlm.nih.gov/pubmed/19250939 En: 30-04-2019.spa
dc.relation.referencesMoudy R, Manning TJ, Beckers CJ. 2001. The Loss of cytoplasmic potassium upon host cell breakdown triggers egress of Toxoplasma gondii. Journal of Biological Chemistry, 276(44), 41492–41501. En: 30-04-2019. http://doi.org/10.1074/jbc.M106154200spa
dc.relation.referencesMüller J, Hemphill A. 2013. New Approaches for the Identification of Drug Targets in Protozoan Parasites. International Review of Cell and Molecular Biology (Vol. 301). Elsevier. http://doi.org/10.1016/B978-0-12-4077041.00007-5spa
dc.relation.referencesMunday BL. 1972. Serological evidence of Toxoplasma infection in isolated groups of sheep. Research in Veterinary Science, 13(1), 100–102.spa
dc.relation.referencesMuñiz S, Mondragón R. 2009. Toxoplasma gondii, un patógeno asesino reemergente. Revista de Educación Bioquímica. 28(2): 52-58.spa
dc.relation.referencesMunoz M, Liesenfeld O, Heimesaat MM. 2011. Immunology of Toxoplasma gondii. Immunological Reviews, 240(1), 269–285. http://doi.org/10.1111/j.1600-065X.2010.00992.xspa
dc.relation.referencesNagamune K, Hicks LM, Fux B, Brossier F, Chini EN, Sibley LD. 2008. Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii. Nature, 451(7175), 207–210. http://doi.org/10.1038/nature06478spa
dc.relation.referencesNichols B and Chiappino ML. 1987. Cytoskeleton of Toxoplasma gondii. Journal Protozoology, 34: 217–26.spa
dc.relation.referencesNicolle C, Manceaux L. 1908. Sur une infection a corps de Leishman (ou organismes voisons) du gondi. C R Academic Science. 147: 736.spa
dc.relation.referencesO’Brien TC, Mackey ZB, Fetter RD, Choe Y, O’Donoghue AJ, Zhou M, McKerrow JH. 2008. A parasite cysteine protease is key to host protein degradation and iron acquisition. Journal of Biological Chemistry, 283(43), 28934–28943. http://doi.org/10.1074/jbc.M805824200spa
dc.relation.referencesO’Donoghue P. 2010. Toxoplasma. En: 30-04-2019. http://parasite.org.au/para-site/text/toxoplasma-text.htmlspa
dc.relation.referencesOkamoto N, Keeling P. 2014. A comparative overview of the flagellar apparatus of dinoflagellate, perkinsids and colpodellids. Microorganisms 2:73–91.doi:10.3390/microorganisms2010073.spa
dc.relation.referencesOIE. (2017). Toxoplasmosis. Capítulo 2.9.9. En: 30-04-2019. http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.09.09_TOXO .pdfspa
dc.relation.referencesOyola LM, Martínez WH, Góngora A, Parra JL. 2006. Encuesta seroepidemiológica transversal a Toxoplasma gondii en médicos veterinarios del municipio de Villavicencio. Meta. Revista ORINOQUIA - Universidad de los Llanos. 50-56.spa
dc.relation.referencesOpsteegh M, Teunis P, Züchner L, Koets A, Langelaar M, van der Giessen J. 2011. Low predictive value of seroprevalence of Toxoplasma gondii in cattle for detection of parasite DNA. International Journal for Parasitology, 41(3), 343–354. http://doi.org/10.1016/j.ijpara.2010.10.006spa
dc.relation.referencesOzgonul C, Besirli CG. 2016. Recent Developments in the Diagnosis and Treatment of Ocular Toxoplasmosis. Ophthalmic Research. Oct 11spa
dc.relation.referencesPaquet C, Yudin MH, Allen VM, Bouchard C, Boucher M, Caddy S, Senikas V. 2013. Toxoplasmosis in pregnancy: prevention, screening, and treatment. Journal of Obstetrics and Gynecology Canada, 35(1), 78–79. http://doi.org/10.1016/S1701-2163(15)31053-7spa
dc.relation.referencesPastorello RG, Costa A da CL, Sawamura MVY, Nicodemo AC, Duarte-Neto AN. 2018. Disseminated toxoplasmosis in a patient with advanced acquired immunodeficiency syndrome. Autopsy and Case Reports, 8(1), 1–8. http://doi.org/10.4322/acr.2018.012spa
dc.relation.referencesPatrón SA, Mondragón M, González S, Ambrosio JR, Guerrero BAL, Mondragón R. 2005. Identification and purification of actin from the subpellicular network of Toxoplasma gondii tachyzoites. International Journal Parasitology 35: 883- 894.spa
dc.relation.referencesPereira-Chioccola VL, Vidal JE, Su C. 2009. Toxoplasma gondii infection and cerebral toxoplasmosis in HIV-infected patients. Future Microbiology, 4(10), 1363–1379. http://doi.org/10.2217/FMB.09.89spa
dc.relation.referencesPersson EK, Agnarson AM, Lambert H, Hitziger N, Yagita H, Chambers BJ, Grandien A. 2007. Death receptor ligation or exposure to perforin trigger rapid egress of the intracellular parasite Toxoplasma gondii. Journal of Immunology, 179(12), 8357–8365. http://doi.org/10.4049/jimmunol.179.12.8357spa
dc.relation.referencesPittman KJ, Knoll LJ. 2015. Long-Term Relationships: the Complicated Interplay between the Host and the Developmental Stages of Toxoplasma gondii during Acute and Chronic Infections. Microbiology Molecular and Biology Rev. Dec; 79(4):387-401. doi: 10.1128/MMBR.00027-15spa
dc.relation.referencesPomares C, Montoya JG. 2016. Laboratory diagnosis of congenital toxoplasmosis. Journal Clinical Microbiology; 54 (10): 2448 54.spa
dc.relation.referencesPomel S, Luk FC, Beckers JM. 2008. Host cell egress and invasion induce marked relocations of glycolytic enzymes in Toxoplasma gondii tachyzoites. PLoS Pathogens, 4(10). http://doi.org/10.1371/journal.ppat.1000188spa
dc.relation.referencesPorchet-Hennere E, Nicholas G. Are rhoptries of coccidian really extrusomes? J. Ultrastruct. Res. 1983, 84:194-203.spa
dc.relation.referencesPutignani L, Mancinelli L, Chierico F, Menichella D, Adlerstein D, Angelici MC, Giangaspero A. 2011. Investigation of Toxoplasma gondii presence in farmed shellfish by nested-PCR and real-time PCR fluorescent amplicon generation assay (FLAG). Experimental Parasitology, 127(2), 409–417. http://doi.org/10.1016/j.exppara.2010.09.007spa
dc.relation.referencesQuan L, Wang ZD, Huang SY, Quang X. 2015. Diagnosis of toxoplasmosis and typing of Toxoplasma gondii. Parasites y vectors. 8:292. En: 03-05-2019. https://doi.org/10.1186/s13071-015-0902-6spa
dc.relation.referencesQue X, Engel JC, Ferguson D, Wunderlich A, Tomavo S, Reed SL. 2007. Cathepsin Cs are key for the intracellular survival of the protozoan parasite, Toxoplasma gondii. Journal of Biological Chemistry, 282(7), 4994–5003. http://doi.org/10.1074/jbc.M606764200spa
dc.relation.referencesQue X, Ngô H, Lawton J, Gray M, Liu Q, Engel J, Brinen L, Ghosh P, Reed SL. 2002. The cathepsin B of Toxoplasma gondii, toxopain-1, is critical for parasite invasion and rhoptry protein processing. Journal of Biological Chemistry, 277(28), 25791–25797. http://doi.org/10.1074/jbc.M202659200spa
dc.relation.referencesRadke JB, Burrows JN, Goldberg DE, Sibley LD. 2018. Evaluation of current and emerging antimalarial medicines for inhibition of Toxoplasma gondii Growth in vitro. ACS Infectious Diseases, 1–23. http://doi.org/10.1021/acsinfecdis.8b00113spa
dc.relation.referencesRaetz M, Hwang SH, Wilhelm CL, Kirkland D, Benson A, Sturge CR, Mirpuri J, Vaishnava S, Hou B, De Franco AL, Gilpin CJ, Hooper LV, Yarovinsky F. 2013. Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFNgamma-dependent elimination of Paneth Cells. Natural Immunology 14:136– 142.doi:10.1038/ni.2508.spa
dc.relation.referencesRajapakse S, Chrishan-Shivanthan M, Samaranayake N, Rodrigo C, Deepika-Fernando S. 2013. Antibiotics for human toxoplasmosis: a systematic review of randomized trials. Pathogens and Global Health, 107(4), 162–169. http://doi.org/10.1179/2047773213Y.0000000094spa
dc.relation.referencesRamírez-Crescencio MA, Velásquez-Pérez L, Ramírez-Crescencio MA, Velásquez-Pérez L. 2013. Epidemiology and trend of neurological diseases associated to HIV/AIDS. Experience of Mexican patients 1995-2009. Clinical Neurology Neurosurgent. Aug; 115(8):1322-5. doi: 10.1016/j.clineuro.2012.12.018.spa
dc.relation.referencesRand AJ, Buck AB, Love PB, Prose NS, Selim MA. 2015. Cutaneous acquired toxoplasmosis in a child: A case report and review of the literature. American Journal of Dermatopathology, 37(4), 305–310. http://doi.org/10.1097/DAD.0000000000000072spa
dc.relation.referencesRiparbelli MG, Cabrera OA, Callaini G, Megraw TL. 2013. Unique properties ofDrosophila spermatocyte primary cilia. Biology Open 2:1137– 1147.doi:10.1242/bio.20135355.spa
dc.relation.referencesRobert-Gangneux F, Dardé ML. 2012. Epidemiology of and diagnostic strategies for toxoplasmosis. Clinical Microbiology Reviews, 25(2), 264–296. http://doi.org/10.1128/CMR.05013-11spa
dc.relation.referencesRobert-Gangneux F, Murat JB, Fricker-Hidalgo H, Brenier-Pinchart MP, Gangneux JP, Pelloux H. 2011. The placenta: a main role in congenital toxoplasmosis? Trends Parasitology. 27:530-6.spa
dc.relation.referencesRodrigues M de L, Deghaide NH, Figueiredo JF, de Menezes MB, Demarco, AL, Donadi E, Fernandes AP. 2016. Toxoplasmic encephalitis: Role of Human Leucocyte Antigens/alleles associated with rapid progression to Acquired Immunodeficiency Syndrome. Brazilian Journal of Infectious Diseases, 20(2), 115–118. http://doi.org/10.1016/j.bjid.2015.10.010spa
dc.relation.referencesRodríguez-Morales AJ. 2016. Zika and microcephaly in Latin America: An emerging threat for pregnant travelers? Travel Medicine and Infectious Disease, 14(1), 5–6. http://doi.org/10.1016/j.tmaid.2016.01.011spa
dc.relation.referencesRoh M, Yasa C, Cho H, Nicholson L, Uchiyama E, Young Y, Sobrin L. 2016. The role of serological titres in the diagnosis of ocular toxoplasmosis. Acta Ophthalmologica, 94(5), 521–522. http://doi.org/10.1111/aos.12851spa
dc.relation.referencesRoiko MS, Svezhova N, Carruthers VB. 2014. Acidification activates Toxoplasma gondii motility and egress by enhancing protein secretion and cytolytic activity. PLoS Pathogens, 10(11). En: 28-04-2019. http://doi.org/10.1371/journal.ppat.1004488spa
dc.relation.referencesRosso F, Agudelo A, Isaza A, Montoya G. 2007. Toxoplasmosis congénita: aspectos clínicos y epidemiológicos de la infección durante el embarazo. Corporación Editora Médica del Valle. Colombia Médica. 38: 316-337.spa
dc.relation.referencesRousseau A, La Carbona S, Dumètre A, Robertson LJ, Gargala G, EscotteBinet S, Aubert D. 2018. Assessing viability and infectivity of foodborne and waterborne stages (cysts/oocysts) of Giardia duodenalis, Cryptosporidium spp., and Toxoplasma gondii: A review of methods. Parasite, 25(14). http://doi.org/10.1051/parasite/2018009spa
dc.relation.referencesRubio CG, Rodríguez R, Pérez D, Kalitovics N, Álvarez F. 2016. Toxoplasmosis ocular adquirida en nuestro medio. Revisión de casos. Artículo original. Archivos de la Sociedad Canaria de Oftalmología; 27: 55-62spa
dc.relation.referencesRyning FW, McLeod R, Maddox JC, Hunt S, Remington JS. 1979. Probable transmission of Toxoplasma gondii by organ transplantation. Annals of Internal Medicine, 90(1), 47–49. http://doi.org/10.7326/0003-4819-90-1-47spa
dc.relation.referencesSaid B, Halsby KD, O’Connor CM, Francis J, Hewitt K, Verlander NQ, Morgan D. 2017. Risk factors for acute toxoplasmosis in England and Wales. Epidemiology and Infection, 145(1), 23–29. En: 28-04-2019. http://doi.org/10.1017/S0950268816002235spa
dc.relation.referencesSanfelice RA, da Silva SS, Bosqui LR, Miranda-Sapla MM, Barbosa BF, Silva, RJ, Costa IN. 2017. Pravastatin and simvastatin inhibit the adhesion, replication and proliferation of Toxoplasma gondii (RH strain) in HeLa cells. Acta Tropical, 167, 208–215. http://doi.org/10.1016/j.actatropica.2016.12.006spa
dc.relation.referencesSang-Eun L, Hong SH, Jeong Y Il, Lee JH, Yoo SJ, Lim HS, Cho SH. 2014. Cross-sectional analysis of the seropositivity and risk factors of Toxoplasma gondii infection among veterinarians, in relation to their public professional activities. Veterinary Parasitology, 203(1–2), 29–34. http://doi.org/10.1016/j.vetpar.2014.01.001spa
dc.relation.referencesScallan E, Hoekstra RM, Angulo FJ, Tauxe RV, Widdowson MA, Roy SL, Jones JL, Griffin PM. 2011. Enfermedades transmitidas por alimentos adquiridas en los Estados Unidos: principales patógenos. Emergent Infection Diseases. 17: 7 - 15. doi: 10.3201 / eid1701.P11101spa
dc.relation.referencesScandizzo H, Bernstein J. 2008. Seroprevalencia de toxoplasmosis en embarazadas del partido de Florencio Varela, Buenos Aires. Argentina. III Congreso Latinoamericano de Zoonosis – VI Congreso Argentino de Zoonosis. Buenos Aires. Argentina. P045. (B1888IQF).spa
dc.relation.referencesSchlundt J, Toyofuku H, Cansen J. 2004. Emerging food-borne zoonoses: Revista science technology. Off. Int. Epiz, 32: 514-533.spa
dc.relation.referencesSchlüter D, Däubener W, Schares G, Groß U, Pleyer U, Lüder C. 2014. Animals are key to human toxoplasmosis. International Journal of Medical Microbiology, 304(7), 917–929. http://doi.org/10.1016/j.ijmm.2014.09.002spa
dc.relation.referencesSchultz TL, Hencken CP, Woodard LE, Posner GH, Yolken RH, JonesBrando L, Carruthers VB. 2014. A thiazole derivative of artemisinin moderately reduces Toxoplasma gondii cyst burden in infected mice. Journal of Parasitology, 100(4), 516–521. http://doi.org/10.1645/13-451.1spa
dc.relation.referencesSharma P, Chitnis CE. 2013. Key molecular events during host cell invasion by Apicomplexan pathogens. Current Opinion in Microbiology, 16(4), 432– 437. http://doi.org/10.1016/j.mib.2013.07.004spa
dc.relation.referencesSheiner L, Santos JM, Klages N, Parussini F, Jemmely N, Friedrich N, Ward GE, Soldati-Favre D. 2010. Toxoplasma gondii transmembrane microneme proteins and their modular design. Molecular Microbiology. 77:912-29.spa
dc.relation.referencesSilveira C, Belfort R, Muccioli C, Abreu MT, Martins MC, Victora C, Holland GN. 2001. A follow-up study of Toxoplasma gondii infection in southern Brazil. American Journal of Ophthalmology, 131(3), 351–354. http://doi.org/10.1016/S0002-9394(00)00830-8spa
dc.relation.referencesSims TA, Hay J, Talbot IC. 1989. An electron microscope and immunohistochemical study of the intracellular location of Toxoplasma tissue cysts within the brains of mice with congenital toxoplasmosis. British Journal Exp Pathology. 70:317–25.spa
dc.relation.referencesSmith DD, Frenkel JK. 1995. Prevalence of antibodies to Toxoplasma gondii in wild mammals of Missouri and East Central Kansas: biologic and ecologic considerations of transmission. Journal of Wildlife Diseases, 31(1), 15–21. http://doi.org/10.7589/0090-3558-31.1.15spa
dc.relation.referencesSinden RE, Talman A, Marques SR, Wass MN, Sternberg MJ. 2010. The flagellum in malarial parasites. Curr Opin Microbiology 13:491– 500.doi:10.1016/j.mib.2010.05.016.spa
dc.relation.referencesSpeer CA, Dubey JP. 2005. Ultrastructural differentiation of Toxoplasma gondii schizonts (types B to E) and gamonts in the intestines of cats fed bradyzoites. International Journal for Parasitology, 35(2), 193–206. En: 3004-2019. http://doi.org/10.1016/j.ijpara.2004.11.005spa
dc.relation.referencesSplendore A. 1908. Un nuovo protozoa parasite dei conigli. (Incontrato nelle lesioni anatomiche d’una malattia che ricorda in molti punti il Kalazar dell’ uomo.) Rev SOG Scientifica Süo Pado 3:109-112.spa
dc.relation.referencesSu C, Evans D, Cole RH, Kissinger JC, Ajioka JW, Sibley LD. 2003. Recent expansion of Toxoplasma through enhanced oral transmission. Science (Vol. 299). http://doi.org/10.1126/science.1078035spa
dc.relation.referencesSuzuki Y, Sa Q, Ochiai E, Mullins J, Yolken R, K.Halonen S. 2014. Cerebral Toxoplasmosis: pathogenesis, host resistance and behavioural consequences. In Toxoplasma gondii (2nd ed., pp. 755–796). Academic Press. http://doi.org/https://doi.org/10.1016/C2011-0-07157-0spa
dc.relation.referencesTenter AM, Heckeroth AR, Weiss LM. 2000. Toxoplasma gondii: From animals to humans. International Journal for Parasitology, 30(12–13), 1217– 1258. http://doi.org/10.1016/S0020-7519(00)00124-7spa
dc.relation.referencesThais FI, Costa GNM, Pacheco IB, Barbosa LG, Santos-Junior CD, Fonseca FPP, Rodrigues VDM. 2016. Expression and partial biochemical characterization of a recombinant serine protease from Bothrops pauloensis snake venom. Toxicon, 115, 49–54. En: 30-04-2019. http://doi.org/10.1016/j.toxicon.2016.03.002spa
dc.relation.referencesTomita T, Yamada T, Weiss LM, Orlofsky A. 2009. Externally triggered egress is the major fate of Toxoplasma gondii during acute infection. The Journal of Immunology, 183(10), 6667–6680. http://doi.org/10.4049/jimmunol.0900516spa
dc.relation.referencesTorgerson PR, Mastroiacovo P. 2013. The global burden of congenital toxoplasmosis: a systematic review. Bulletin of the World Health Organization, 91(7), 501–508. http://doi.org/10.2471/BLT.12.111732spa
dc.relation.referencesTorrey EF, Yolken RH. 2013. Toxoplasma oocysts as a public health problem. Trends in Parasitology, 29(8), 380–384. http://doi.org/10.1016/j.pt.2013.06.001spa
dc.relation.referencesUeno N, Harker KS, Clarke EV, McWhorter FY, Liu WF, Tenner AJ, Lodoen MB. 2014. Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers. Cellular Microbiology. 16:580–595. doi:10.1111/cmi.12239spa
dc.relation.referencesUribe L, Lora F, Acosta J, Gómez J. 2011. Amplificación de los genes rop 18, GRA6 y BTUB deToxoplasma gondii mediante la técnica de PCR en carnes de consume humano. Biomédica, 31(Suplemento 3), 209-421.spa
dc.relation.referencesVarela RE. 2016. Glosario de términos de Parasitología. Retrieved from http://aprendeenlinea.udea.edu.co/lms/moodle/mod/glossary/view.php?id=10 1076ymode=dateyhook=ysortkey=CREATIONysortorder=ascyfullsearch=0yp age=2spa
dc.relation.referencesVidadala RSR, Rivas KL, Ojo KK, Hulverson MA, Zambriski JA, Bruzual I, Maly, DJ. 2016. Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis. Journal of Medicinal Chemistry, 59(13), 6531–6546. http://doi.org/10.1021/acs.jmedchem.6b00760spa
dc.relation.referencesVieira N, Losano JD, Angrimani D, Kawai GK, Bicudo L, Rui BR, Nichi M. 2018. Induced sperm oxidative stress in dogs: Susceptibility against different reactive oxygen species and protective role of seminal plasma. Theriogenology, 108, 39–45. http://doi.org/10.1016/j.theriogenology.2017.11.020spa
dc.relation.referencesVijaykumar BR, Lekshmi SU, Sai Kant R, Vaigundan D, Mahadevan A, Rajendran C, Jayshree RS. 2016. Genetic characterization of Toxoplasma gondii from autopsy proven cases of AIDS associated cerebral toxoplasmosis in South India. Infection, Genetics and Evolution, 39, 106–112. http://doi.org/10.1016/j.meegid.2016.01.014spa
dc.relation.referencesVillard O, Cimon B, L’Ollivier C, Fricker-Hidalgo H, Godineau N, Houze S, Candolfi E. 2016a. Help in the choice of automated or semiautomated immunoassays for serological diagnosis of toxoplasmosis: Evaluation of nine immunoassays by the French National Reference Center for Toxoplasmosis. Journal of Clinical Microbiology, 54(12), 3034–3042. http://doi.org/10.1128/JCM.01193-16spa
dc.relation.references______. 2016b. Serological diagnosis of Toxoplasma gondii infection. Recommendations from the French national reference center for toxoplasmosis. Diagnostic Microbiology and Infectious Disease, 84(1), 22–33. http://doi.org/10.1016/j.diagmicrobio.2015.09.009spa
dc.relation.referencesWallace GD. 1969. Serologic and epidemiologic observations on toxoplasmosis on three Pacific Atolls. American Journal of Epidemiology, 90(2), 103–111. http://doi.org/doi.org/10.1093/oxfordjournals.aje.a121054spa
dc.relation.referencesWei HX, Wei SS, Lindsay DS, Peng HJ. 2015. A systematic review and meta- analysis of the efficacy of anti-Toxoplasma gondii medicines in humans. PLoS ONE, 10(9), 1–12. En: http://doi.org/10.1371/journal.pone.0138204spa
dc.relation.referencesWeiss LM, Dubey JP. 2009. Toxoplasmosis: A history of clinical observations. International Journal for Parasitology, 39(8), 895–901. En: 30-04-2019. http://doi.org/10.1016/j.ijpara.2009.02.004spa
dc.relation.referencesWilking H, Thamm M, Stark K, Aebischer T, Seeber F. 2016. Prevalence, incidence estimations, and risk factors of Toxoplasma gondii infection in Germany: A representative, cross-sectional, serological study. Scientific Reports, 6(February), 1–9. http://doi.org/10.1038/srep22551spa
dc.relation.referencesWinkel KD, Saw TH, Prociv P. 1990. Risk of parasitic infections from sandpits. Medical Journal of Australia, 153(8), 503–9.spa
dc.relation.referencesWolf A, Cowen D. 1937. Granulomatous encephalomyelitis due to encephalito- zoon (Encephalitozoie encephalomyelitis). A new protozoan disease of men. Bull Neurology Institute New York. 6: 306.spa
dc.relation.referencesWood CR, Huang K, Diener DR, Rosenbaum JL. 2013. The cilium secretes bioactive ectosomes. Curr Biol23:906–911.doi:10.1016/j.cub.2013.04.019.spa
dc.relation.referencesZamora A, Cuadrado S, Triviño J, Moncada DM, Lora F, Gómez JE. 2016. Diversidad Genética Y Filogenia De Toxoplasma Gondii A Partir De Secuencias Parciales De B1 De Colombia Y Otros Países. Revista de la Asociación Colombiana de Ciencias Biológicas, 2016; 28: 8-15.spa
dc.relation.referencesZhang X, Jin L, Cui Z, Zhang C, Wu X, Park H, Jin C. 2016. Antiparasitic effects of oxymatrine and matrine against Toxoplasma gondii in vitro and in vivo. Experimental Parasitology, 165, 95–102. http://doi.org/10.1016/j.exppara.2016.03.020spa
dc.relation.referencesZhu C, Cui L, Zhang L. 2012. Comparación de un ELISA comercial con la prueba de aglutinación modificada para la detección de anticuerpos de Toxoplasma gondii en sueros de perros y gatos infectados naturalmente. Iran Journal Parasitology; 7: 89–95.spa
dc.rightsDerechos Reservados - Universidad de los Llanos, 2019spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.subject.armarcEnfermedades transmitidas por animales
dc.subject.armarcEnfermedades zoonóticas
dc.subject.armarcEnfermedades transmisibles
dc.subject.proposalToxoplasma gondiispa
dc.subject.proposalZoonóticaspa
dc.subject.proposalFelinosspa
dc.subject.proposalDistribución mundialspa
dc.subject.proposalWorldwide distributionspa
dc.titleToxoplasmosis, una parasitosis de importancia en salud públicaspa
dc.typeTrabajo de grado - Pregradospa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1fspa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/bachelorThesisspa
dc.type.redcolhttps://purl.org/redcol/resource_type/TPspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dspace.entity.typePublication

Archivos

Bloque original
Mostrando 1 - 2 de 2
Cargando...
Miniatura
Nombre:
121002118
Tamaño:
1.27 MB
Formato:
Adobe Portable Document Format
Descripción:
Trabajo de grado
Cargando...
Miniatura
Nombre:
Anexo 1
Tamaño:
632.43 KB
Formato:
Adobe Portable Document Format
Descripción:
Carta de autorización
Bloque de licencias
Mostrando 1 - 1 de 1
Cargando...
Miniatura
Nombre:
license.txt
Tamaño:
14.43 KB
Formato:
Item-specific license agreed upon to submission
Descripción: